Welcome to 2 Sisters 4 Brothers Restaurant & Lounge
Nestled in the heart of East Harlem, 2 Sisters 4 Brothers Restaurant & Lounge offers a vibrant dining experience that delights both the palate and spirit. With a menu featuring tantalizing dishes like Jerk Chicken and Salmon Cakes, the flavors transport you to a culinary paradise. Guests rave about the inviting ambiance, complemented by exceptional service and a lively atmosphere, ideal for social gatherings. Signature sides, such as creamy Macaroni & Cheese and fresh Spinach, round out a satisfying meal. Whether you're enjoying a drink during happy hour or celebrating a special occasion, this lounge is the perfect blend of delicious food and enjoyable vibes.
- 355 E 116th St, New York, NY 10029, United States355 E 116th St, New York, NY 10029, United States Hotline: +1 646-858-0051
Welcome to 2 Sisters 4 Brothers Restaurant & Lounge, a vibrant culinary haven located in the heart of East Harlem at 355 E 116th St, New York, NY 10029. This restaurant and lounge seamlessly blends delectable food, refreshing drinks, and an inviting atmosphere perfect for social gatherings. Here, every visit promises not just a meal but a delightful experience, where the rich flavors of the Caribbean and American cuisine take center stage.
The menu offers a tantalizing selection that caters to diverse palates. From the savory Turkey Sliders ($16) to the mouthwateringly crispy Wings & Fries ($15), diners can expect comfort food with a twist. Seafood lovers will delight in dishes like the Salmon Bites available in Teriyaki or Honey Glaze ($19), while those craving something hearty can indulge in the decadent Alfredo with Chicken or Shrimp ($17). And for a true taste of the South, the macaroni and cheese ($8.96) comes highly recommended.
However, it’s not just the food that captures the hearts of patrons. The lounge creates an ambiance that is described as cozy and welcoming, featuring attentive bartenders and a soundscape that invokes nostalgia with hits from the late 90s and early 2000s, further enhancing the dining experience. Guests have expressed their satisfaction with the excellent service and the overall atmosphere—an essential aspect of the 2 Sisters 4 Brothers experience.
Moreover, Friday evenings bring about a lively happy hour, enticing patrons with specials like the henny punch—buy one, get one free! The blend of great drinks and upbeat music makes it a perfect start to the weekend. Yet, customer feedback also highlights areas for improvement, underscoring the importance of consistent service to maintain the vibrant reputation this restaurant has garnered.
Whether you’re looking for a place to unwind after a long day or to celebrate a special occasion, 2 Sisters 4 Brothers Restaurant & Lounge offers an inviting space with friendly prices and a diverse menu. The venue thrives on making each guest feel appreciated and valued, with enthusiastic staff keen to ensure your experience is nothing short of excellent.
For reservations or inquiries, feel free to reach out at +1 646-858-0051. Indulge in the flavorful journey that awaits at 2 Sisters 4 Brothers—you won’t be disappointed!

Miracle was very welcoming from the door. The service & entertainment was fast & top tier! I will be back soon.

Went during the start of happy hour on a Friday. Sat at the bar and got 2 henny punch. Buy one, get one free, and it didn't disappoint. Wings and fries was also good. Music was more late 90s, early 2000s but it was good music from then. Nice spot

I love this spot!!!! However... There's this trash working there on Tuesday and Sunday her name is Maya.... (Don't go those days) She's rude, disrespectful, always got an attitude and makes you feel like it's NOT a pleasure to serve you. ALL those stars and not one for her. If I based it on my experience with her??? ZERO!!! It's affecting me. Just knowing she's allowed to be there... At all. Buhbye MAYA you are horrible!!!

Loved it! Very attentive bartenders. Everyone was very pleasant. The music was on point. Only comment: we had to wait at least 20 min for a hookah other than that this place is great. Me n my ppl enjoyed ourselves. I would def go back.

This lounge is on point, as it is inviting, friendly, cozy and safe. The food is on point. The service is amazing. Staff friendly and courteous. Drinks done well. DJ’s always on top of their game. Music is excellent.... Security on point!!!! An atmosphere for the grown, sexy and classy. Vibes very nice. Thank you for allowing me to celebrate my birthday and hosting my Paint & Sip... it was absolutely amazing...

The food was great . I had sweet chili wings with fries. The drinks were strong and the dj was great. It is definitely a vibe. I’m going back to try their Rasta pasta this week.

I visited this restaurant & lounge last night and I must say the service was great and the food was amazing! I had the shrimp and it was seasoned & cooked to perfection. So good I ordered another serving. The music was good & the atmosphere was very inviting and relaxing. The set up is perfect! Great place to have a party. The employees are pleasant from the bartenders to the waiters & waitresses.. Not to mention the owners.. Definitely a go to spot in Harlem!

Wow, such an inspiring place. To see a family start and manage a business is quite beautiful. If you ever want to come hang out and have a drink and a hookah with some good food, this is the place. If you ever want to have bottle service and celebrate a birthday and have like a club vibe, then this is the place. I love the owners and the staff and highly recommend these guys for any type of vibe your looking for. The hookah is great, the drinks are bomb and the food is just to die for! Sundays are like a pop-up shop vibe with some of the staff even sharing their own brands and promoting other black owned businesses. Its such a beautiful thing. The world should make it their business to at least visit this place once. You gotta be there!